Assessing complications following pancreatoduodenectomy: the Comprehensive Complication Index versus the Clavien-Dindo classification.

ABSTRACT:

Background

This study aimed to compare the accuracy of the Comprehensive Complication Index (CCI) with that of the Clavien-Dindo classification in patients undergoing pancreatoduodenectomy.

Methods

A two-centre, retrospective study was undertaken that included patients who underwent pancreatoduodenectomy between 2008 and 2022. Three approaches were used to assess the two complication scores: the Spearman rank test, yielding the correlation coefficient (r), the area under the curve with 95% confidence intervals, and a mixed-effects model and a generalized mixed-effects model that yielded odds ratios and β-coefficients.

Results

A total of 596 patients were included. The CCI and Clavien-Dindo classification demonstrated no correlation with 90-day mortality (r = - 0.021,

SUBMITTER: Ukegjini K 

PROVIDER: S-EPMC12822778 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature