Assessing Agreement of Intraocular Pressure from Four Mechanistically Different Tonometers in the Eye Dynamics and Engineering Network Clinical Trial.

ABSTRACT:

Purpose

To compare the measurements of intraocular pressure (IOP) by four mechanistically different tonometers in healthy participants from the Eye Dynamics and Engineering Network Aqueous Humor Dynamics clinical trial using the mean difference estimation, equivalence statistics, and adjusting for proparacaine's effects on IOP.

Design

Multicenter open-label clinical trial in healthy adults (NCT01677507).

Participants

Enrolled were 122 participants (55.2 ± 8.8 years; 92 women and 30 men), 121 of which had measurements with and without proparacaine.

Methods

Participants from 3 sites had their IOPs measured with iCare rebound tonometer (RT), ocular response analyzer corneal-compensated (CC), pneumatonometer (PN), and Goldmann applanation tonometer (GAT). Intraocul

SUBMITTER: Liu M 

PROVIDER: S-EPMC12822827 | biostudies-literature | 2026 Jan-Feb

REPOSITORIES: biostudies-literature