Polymerization of hydroxyethyl methacrylate (HEMA) under rotation to form core-annular hydrogels.

ABSTRACT:

Hypothesis

We propose to polymerize high water content hydroxyethyl methacrylate (HEMA) formulations in a rotating cylinder to explore the effect of the rotation on microstructure and critical parameters such as diffusivity of model proteins in porous poly-HEMA gels.

Experiments

Cylindrical molds were partially filled with water-HEMA-initiator-crosslinker mixtures and exposed to UV light while undergoing rotation to polymerize into a cylindrical tube. The process was repeated multiple times to manufacture a core annular rod with multiple concentric rings, in which at least one ring was porous. The porous gels were imaged by scanning electron microscopy to explore the microstructure. The transport of model proteins bovine serum albumin and human γ-globulin was measured and mo

SUBMITTER: Sparks Z 

PROVIDER: S-EPMC12822855 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature