Comparative analysis of Buruli ulcer in Ghana and Cote d'Ivoire: A cross-sectional study.

ABSTRACT: Buruli ulcer (BU), caused by Mycobacterium ulcerans, is a neglected tropical skin disease highly endemic in West Africa and Australia. The molecular diversity of M. ulcerans strains varies geographically within endemic regions and this directly influences the virulence of mycolactone, the lipid toxin produced by the bacterium which is responsible for disease pathogenesis. This study investigated differences in BU presentation based on various sociodemographic determinants of infection between Ghana and Côte d'Ivoire, two of the most affected countries globally. While the general epidemiology and presentation of confirmed Buruli ulcer cases were similar in both countries, distinct differences emerged in clinical manifestation, perceived transmission routes, and health-seeking behaviours. In

SUBMITTER: Gyamfi E 

PROVIDER: S-EPMC12822952 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature