Altered coagulation and platelet indices in Yemeni patients with type 2 diabetes mellitus: A conflict-affected population.

ABSTRACT: Type 2 diabetes mellitus (T2DM) is associated with a prothrombotic state; however, its hemostatic profile in conflict-affected populations remains poorly characterized. This study aimed to evaluate coagulation parameters and platelet indices among Yemeni adults with T2DM and to correlate these markers with glycemic control. A case-control study was conducted on 140 T2DM patients and 100 age- and sex-matched non-diabetic controls in Aden, Yemen. Prothrombin time (PT), activated partial thromboplastin time (APTT), mean platelet volume (MPV), and platelet distribution width (PDW) were measured using standardized analyzers (STA-R Evolution and Sysmex XN-550). Glycemic control was assessed via HbA1c. Poor glycemic control (HbA1c ≥ 7%) was observed in 86% of patients. T2DM patients exhibited a d

SUBMITTER: Ali NT 

PROVIDER: S-EPMC12822953 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature