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Physical Activity Is Inversely Associated with Clinical Exacerbation in Patients with Crohn's Disease in Remission: A Prospective Cohort Study.


ABSTRACT:

Introduction: Physical activity (PA) is associated with improved quality of life in patients with Crohn's disease (CD). However, evidence of its impact on the clinical course of the disease remains limited. We aimed to evaluate the association between PA and relapse incidence in patients with CD in clinical remission and its association with patient-reported outcome measures.

Methods

A prospective cohort study of adult patients with CD in clinical remission was followed-up for 1 year or until relapse. At baseline, participants completed PA and nutritional questionnaires, and a patient-reported outcomes measurement information system. Multivariable Cox proportional hazards models assessed the association between PA and relapse risk, adjusted for confounders including fecal calprot

SUBMITTER: Sarbagili-Shabat C 

PROVIDER: S-EPMC12823096 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature