Association of changes in body weight and waist circumference with a subsequent risk of developing hypertension in men requiring specific healthcare guidance.

ABSTRACT: Although body weight (BW) and waist circumference (WC) reduction are key goals of Japan's Specific Health Guidance program, limited evidence exists linking these reductions to a lower incidence of hypertension. This study aimed to evaluate the association between changes in BW and WC and the subsequent development of hypertension among men in a nationwide population. We retrospectively analyzed 23,109 men aged 40-64 years who required intensive health guidance and had no prior history of hypertension, using a nationwide database (DeSC Healthcare, Tokyo, Japan) from April 2014 to August 2023. One-year changes in BW and WC were examined for their association with incident hypertension using multivariable Cox regression and cubic spline analyses. During a mean follow-up of 1381 ± 789 days, 41

SUBMITTER: Kitani Y 

PROVIDER: S-EPMC12823394 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature