The impact of cachexia index combined with BMI trajectory on survival outcomes in patients with cancer cachexia.

ABSTRACT:

Background

The cachexia index (CXI) has emerged as a recognized prognostic biomarker of cancer cachexia. However, the dynamic progression of cachexia may not be fully captured by a single assessment. This study examined the impact of integrating the CXI with BMI trajectories on the survival prognosis of patients with cancer cachexia to enable early identification of high-risk populations.

Methods

This is a retrospective review of clinical and pathological data from 147 patients diagnosed with cancer cachexia at Xuzhou Central Hospital between January 2019 and May 2024. Based on computed tomography images at the time of initial cancer cachexia diagnosis to calculate the L3-SMI, the CXI was calculated using serum albumin (ALB) level, neutrophil-to-lymphocyte ratio (NLR), and s

SUBMITTER: Cheng X 

PROVIDER: S-EPMC12823498 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature