Effectiveness and safety of four drainage methods for lung abscess: a Bayesian network meta-analysis and systematic review.

ABSTRACT:

Objective

To compare the efficacy and safety of various pus drainage methods for lung abscess via network meta-analysis.

Methods

Randomized controlled trials (RCTs) from PubMed, Embase, Scopus, Web of Science, VIP, Wanfang, and CNKI were searched up to April 2025. Study quality was assessed using the Cochrane Risk of Bias Tool (v5.4.0). Bayesian network meta-analysis was conducted using Rstudio (v4.4.1).

Results

A total of 23 RCTs (1,453 patients) evaluating four drainage techniques were included. Effective rate: CT-guided percutaneous drainage + antibiotics ranked highest (77% probability), outperforming antibiotics alone (OR = 5.4) and conventional postural drainage + antibiotics (OR = 7.4). Hospital stay: Ultrasound-guided drainage + antibiotics ranked best (89% pr

SUBMITTER: Zhang X 

PROVIDER: S-EPMC12823804 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature