Orally administered fluorescein angiography for ultra-wide-field imaging: is a safe and effective modality across different age groups and fundus diseases?

ABSTRACT:

Purpose

To comprehensively evaluate the clinical utility, imaging performance, and safety of orally administered fluorescein angiography (oral FA) combined with an ultra-wide-field imaging system in the diagnosis and management of fundus disorders.

Methods

This prospective study enrolled 382 patients (676 eyes) aged 4-83 years, comprising 164 females and 218 males. All participants underwent oral FA after ingesting a weight-based dose of fluorescein sodium. Anonymized peak-phase images were independently graded by four retina specialists using a standardized three-parameter scoring system. Images were classified as high, moderate, or poor quality based on total scores. Circulation times (first appearance time, detailed visualization time, and optimal visualization time) and

SUBMITTER: Ji Y 

PROVIDER: S-EPMC12823843 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature