Development and validation of a prognostic nomogram for predicting ventilator-associated pneumonia risk in elderly large vessel occlusion ischemic stroke after endovascular therapy patients.

ABSTRACT:

Background

Acute ischemic stroke with large vessel occlusion (AIS-LVO) poses a grave threat to the health of the elderly, exhibiting a high degree of disability and mortality. Post-stroke ventilator-associated pneumonia (VAP) significantly impairs neurological recovery and worsens clinical outcomes. This study aimed to construct and validate a prognostic nomogram to forecast VAP risk in elderly patients who underwent endovascular therapy (EVT) with AIS-LVO.

Methods

We retrospectively analyzed a total of 536 patients with AIS-LVO who endured EVT under mechanical ventilation at the Dongguan Hospital of Guangzhou University of Chinese Medicine from August 2018 to March 2025. After applying inclusion/exclusion criteria, 240 elderly patients were randomly split into two groups: t

SUBMITTER: Liang W 

PROVIDER: S-EPMC12823881 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature