Prognostic value of neutrophil to lymphocyte ratio in patients with aortic dissection: a systematic review and meta-analysis.

ABSTRACT:

Background

Aortic dissection (AD) is a highly fatal cardiovascular condition, with mortality exceeding 50% within the first 24 h and postoperative mortality approaching 30%. Inflammatory mechanisms have been implicated in AD pathogenesis, but the prognostic value of the neutrophil-to-lymphocyte ratio (NLR) remains uncertain. This study aimed to synthesize available evidence on NLR as a predictor of adverse outcomes in AD and to inform hypotheses for future research.

Methods

Following PRISMA 2020 guidance, a systematic search was conducted in Web of Science, PubMed, Embase, and the Cochrane Library through December 2024. Study selection, data extraction, and quality assessment were performed independently by two reviewers. Pooled odds ratios (ORs) and 95% confidence intervals

SUBMITTER: Li L 

PROVIDER: S-EPMC12823981 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature