Effectiveness of exercise interventions on androgen and sex hormone-binding globulin levels in women with polycystic ovary syndrome: a systematic review and meta-analysis.

ABSTRACT:

Introduction

Polycystic ovarian syndrome (PCOS) is a common disorder typified by hyperandrogenism, ovarian dysfunction, and metabolic disorders. Elevated androgen and decreased Sex Hormone Binding Globulin (SHBG) levels are some of the main features contributing to its clinical manifestations. Lifestyle interventions, especially exercise, are considered first-line management methods due to their positive effects on hormonal regulation. Due to a lack of comprehensively synthesized data on the effects of exercise on androgen and SHBG levels, in this systematic review and meta-analysis, we aimed to evaluate the effects of structured exercise on Total Testosterone and Dehydroepiandrosterone (DHEA-S) as primary parameters, and SHBG levels as secondary parameters.

Methods

Relevant

SUBMITTER: Atmaca L 

PROVIDER: S-EPMC12824002 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature