Clinical and Prognostic Factors of Submandibular Gland Malignancies: A SEER-Based Analysis : Analysis of Submandibular Gland Tumors.

ABSTRACT:

Objective

While neoplasms of the submandibular gland (SMG) are rare, there is a nearly 50% risk of malignancy and its neoplasms are associated with poorer prognoses. Due to the rarity of these tumors, clinical and prognostic information relating to these tumors is limited; we aimed to elucidate these factors using an analysis of the Surveillance, Epidemiology, and End Results (SEER) database.

Methods

A retrospective population-based analysis was performed with data regarding primary SMG malignancy from 2000 to 2019 as extracted from the SEER database. Kaplan-Meier curves and log-rank tests assessed differences in survival by tumor grade and treatment. To estimate odds of death, Royston-Parmar Proportional Odds models were used. Stratified analyses were conducted by tumor sta

SUBMITTER: Arya P 

PROVIDER: S-EPMC12824069 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature