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Association Between Atopic Dermatitis and Systemic Immune-Inflammation Index: Evidence From NHANES 1999-2006.


ABSTRACT:

Background

Clinical studies have demonstrated that the systemic immune-inflammation index (SII) is widely used to assess immunity and inflammation in patients. However, the association between SII and atopic dermatitis (AD) remains unclear. This study, based on the National Health and Nutrition Examination Survey (NHANES) database, aims to explore the relationship between SII and AD.

Methods

This study utilized NHANES data from 1999 to 2006, with a total of 8194 subjects included in the final analysis. We examined the associations between AD, SII, and other covariates by analyzing baseline characteristics and performing correlation analyses. Multivariate generalized linear models (GLMs) were used to analyze the correlation between AD and SII risk. A weighted multivariate log

SUBMITTER: Han J 

PROVIDER: S-EPMC12824450 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature