Marked Reduction in HIV/HCV Coinfections in Iceland Following the TraP HepC Nationwide Hepatitis C Elimination Program.

ABSTRACT:

Background

The nationwide Treatment as Prevention program for Hepatitis C (TraP HepC) was initiated in Iceland in 2016, where direct-acting antivirals (DAAs) replaced interferon-based treatments for hepatitis C virus (HCV). The study aimed to assess the impact of TraP HepC on the epidemiology of HIV/HCV coinfection, the cascade of care, and HCV reinfection rates among coinfected individuals.

Methods

A nationwide retrospective study was conducted on all people with HIV in Iceland who tested HCV antibody positive during 2000-2020. Medical records, laboratory results, and treatment outcomes were reviewed and analyzed by treatment era: interferon (2000-2015) and DAA (2016-2020).

Results

Out of 648 people with HIV, 78 were HCV antibody positive during 2000-2020, of whom 61

SUBMITTER: Hlynsdottir K 

PROVIDER: S-EPMC12824461 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature