Canine <i>Providencia alcalifaciens</i>: virulence factors and phylogenetic analysis of an emerging enteropathogen.

ABSTRACT: In 2019, an outbreak of acute haemorrhagic diarrhoea (AHD) in dogs in Norway was linked to Providencia alcalifaciens. A marked increase in diarrhoeal cases in dogs during the autumn, along with the frequent identification of P. alcalifaciens in affected dogs, supports its role as a causative agent in seasonal diarrhoea in dogs in Norway. Previous phylogenetic studies have revealed two major genetic lineages of P. alcalifaciens, one of which is associated with diarrhoeal disease and carries a plasmid-borne type 3 transport system (T3SS_1a). The aim of this study was to place Norwegian P. alcalifaciens isolates in a global phylogenetic context and to characterize the distribution of putative virulence-associated genes (VAGs) in isolates from dogs with AH

SUBMITTER: Soltvedt EM 

PROVIDER: S-EPMC12824644 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature