Human Metapneumovirus and Respiratory Syncytial Virus in Children: A Comparative Analysis.

ABSTRACT:

Background

Human metapneumovirus (HMPV) and respiratory syncytial virus (RSV) are genetically related viruses and major causes of medically attended acute respiratory illness in children. Research comparing the severity of illnesses resulting from these infections lacks consensus.

Methods

Children younger than 18 years with acute respiratory illness were enrolled through active, prospective surveillance from 2016 to 2020 at 7 US pediatric hospitals and emergency departments (EDs). Clinical information was obtained from parent interviews and medical records. Midturbinate nasal swabs were collected and tested for RSV and HMPV using molecular diagnostic assays at each site. We compared descriptive and clinical features of children with RSV or HMPV and calculated adjusted odds r

SUBMITTER: Goldstein LA 

PROVIDER: S-EPMC12824835 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature