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Association between stress hyperglycemia ratio and all-cause mortality among ICU patients with sepsis: a systematic review and meta-analysis.


ABSTRACT:

Background

The stress hyperglycemia ratio (SHR) is defined as the admission blood glucose level divided by the estimated average glucose derived from glycated hemoglobin (HbA1c). Previous studies have demonstrated that higher SHR levels are associated with increased all-cause mortality among intensive care unit (ICU) patients. However, the relationship between SHR and mortality risk specifically in patients with sepsis remains controversial.

Objectives

This study aimed to systematically evaluate, through a systematic review and meta-analysis, the association between SHR and all-cause mortality among adult ICU patients with sepsis.

Methods

A comprehensive search was performed in PubMed, Web of Science, Embase, and the Cochrane Library databases. The methodological qual

SUBMITTER: Xie H 

PROVIDER: S-EPMC12825456 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature