Impact of foetal growth restriction and being born small for gestational age on newborn echo- and electrocardiographic measurements-a Copenhagen baby heart study.

ABSTRACT:

Aims

Foetal growth restriction (FGR) and being born small for gestational age (SGA) have been linked to later cardiovascular disease. We examined the impact of FGR and SGA on neonatal echo- and electrocardiographic measurements in the Copenhagen Baby Heart Study.

Methods and results

The study included 26 175 newborns. Infants with FGR (n = 1020) and SGA (n = 2328) were compared to infants born appropriate for gestational age using linear regression with adjustment for body size, age at examination, sex, and gestational age at birth. FGR and SGA were associated with reduced left ventricular (LV) internal diameters in end-systole [adjusted mean difference (aMD) -0.09 mm, 95% confidence interval (CI) -0.18,0.01, and -0.12 mm, 95% CI -0.19, -0.06, respectively] and

SUBMITTER: Norskov EH 

PROVIDER: S-EPMC12825605 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature