Measurement of turbulent kinetic energy with colour Doppler echocardiography and particle tracing velocimetry in an ex-vivo aortic stenosis model.

ABSTRACT:

Introduction

Grading of aortic stenosis (AS) is paramount to determine the ideal timing for aortic valve replacement. However, echocardiographic assessment of AS is challenging and subject to inaccuracy. Increased turbulent kinetic energy (TKE) in the aorta, created by a restricted opening stenotic aortic valve, could serve as a new marker for assessing AS severity. However, in this contest, TKE evaluated with ultrasound colour Doppler have not yet been clinically validated.

Methods and results

Porcine aortic valves were tested ex-vivo in a left heart mock loop under various flowrates (1, 2.5, and 4 L/min) and three stiffness grades (SGa, SGb, SGc as native, stiffer, and stiffest stiffness grade, respectively). Reference TKE values were obtained using backlight particle trac

SUBMITTER: Buffle E 

PROVIDER: S-EPMC12825612 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature