Efficacy and safety of Wenxin Keli for ventricular premature beat: An overview of systematic reviews and meta-analyses.

ABSTRACT:

Background

Wenxin Keli (WXKL) is a common medication used to treat ventricular premature beat (VPB). As a complementary alternative therapy, the clinical efficacy and safety of WXKL-assisted treatment of VPB has been reported by several systematic reviews (SRs), but the quality of evidence has not been systematically reviewed.

Methods

We conducted a literature search on 7 databases until May 1, 2025. Risk of bias in systematic was used to assess the risk of bias in SRs. A measurement tool to Assess Systematic Reviews 2 was used to evaluate the methodological quality of the SRs, respectively. Grading of recommendations assessment, development and evaluation (GRADE) was used to evaluate the quality grading of outcomes.

Results

Eleven SRs, including 211 clinical randomiz

SUBMITTER: Zhou X 

PROVIDER: S-EPMC12826144 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature