Self-reported sleep quality and frailty in middle-aged people living with HIV in an African setting: a pilot study.

ABSTRACT: People living with HIV (PLWH) are at increased risk of frailty, yet the role of sleep disturbances in this risk remains underexplored. In this cross-sectional study, we aimed to evaluate self-reported sleep quality in PLWH and relevance to frailty in a high HIV-prevalence setting within Africa. We enrolled 50 PLWH on suppressive antiretroviral therapy (age: 56.9 ± 4.4 years; 26 females) and 50 matched HIV-seronegative controls (age: 56.6 ± 4.3 years; 24 females) in Botswana. Sleep quality was scored subjectively as "good" or "poor" based on participants' responses to two self-reported sleep questions. The frailty index was constructed based on thirty-three health deficits related to body mass index, waist circumference, physical activity, emotional status, and fatigue, and scored ranging b

SUBMITTER: Zheng X 

PROVIDER: S-EPMC12826803 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature