Relations of Artificial Intelligence Vascular Age With Cardiometabolic Disease Progression: The Framingham Heart Study.

ABSTRACT:

Background

Aortic stiffening increases pulsatile power transmission into the microvasculature, resulting in blunted microvascular reactivity, which can impair postprandial nutrient processing and glucose homeostasis. Cardiometabolic disease (CMD) contributes to aortic stiffening and risk for major cardiovascular disease events. Our goal was to assess potential bidirectional relations of aortic stiffness with CMD progression.

Methods

Relations of artificial intelligence vascular age (AI-VA), a measure of aortic stiffness, with new-onset hypertension, diabetes, obesity, and lipid abnormalities were assessed in 7188 Framingham Heart Study (FHS) participants by using Cox proportional hazards regression. Short-term bidirectional relations of AI-VA with key continuous cardiometabo

SUBMITTER: Hamel-Sellman DJ 

PROVIDER: S-EPMC12826898 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature