Characteristics and Long-Term Outcome of Acute Ischemic Stroke in Patients With Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy Compared With Sporadic Small Vessel Occlusion.

ABSTRACT:

Background

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) often presents as acute ischemic stroke involving cerebral perforators. This study compared the clinical and imaging characteristics and stroke recurrence between patients with CADASIL and those with sporadic small vessel occlusion.

Methods

We retrospectively analyzed 70 patients with CADASIL and 70 age- and sex-matched patients with sporadic small vessel occlusion, all of whom experienced acute ischemic stroke. Clinical characteristics and imaging findings were compared, and factors associated with stroke recurrence over a 10-year follow-up period were assessed using Cox proportional hazards models.

Results

Patients with sporadic small vessel occlusion had

SUBMITTER: Ha SH 

PROVIDER: S-EPMC12826917 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature