Differential Effects of Admission Hemoglobin A_1c by Estimated Glomerular Filtration Rate Stages on Mortality in Acute Ischemic Stroke and Diabetes.

ABSTRACT:

Background

The relationship between admission hemoglobin A_1c (HbA_1c) levels, estimated glomerular filtration rate (eGFR) stages, and early outcomes may provide key insights into the need for individualized glycemic control based on kidney function in patients with ischemic stroke and diabetes.

Methods

We analyzed data from a multicenter, nationwide, prospective stroke registry in South Korea, including patients with ischemic stroke within 7 days of onset and diabetes. Admission HbA_1c levels (prestroke glycemic status) were categorized as <6.0%, 6.0% to 7.0%, 7.0% to 8.0%, and ≥8.0%. eGFR stages were classified from stage 1 to stage 5 based on the Kidney Disease: Improving Global Outcomes 2021 guidelines. The primary outcome was 3-month all-ca

SUBMITTER: Kim JT 

PROVIDER: S-EPMC12826925 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature