Progression of immunoglobulin A nephropathy (IgAN) in a Hispanic/Latinx population in the United States.

ABSTRACT:

Background

Immunoglobulin A nephropathy (IgAN) is a leading cause of chronic kidney disease (CKD) worldwide. While racial and ethnic differences in disease progression are well documented, the Hispanic/Latinx populations remain understudied despite their elevated risk of kidney failure among other CKD populations.

Objective

This study aimed to evaluate the kidney function decline and progression in Hispanic/Latinx patients with biopsy-proven IgAN within a large, integrated healthcare system and to contextualize to other racial/ethnic groups.

Methods

We conducted a retrospective case series study of 259 Hispanic/Latinx adults with biopsy-proven IgAN from the Kaiser Permanente Southern California (KPSC) health system. Patients were followed from biopsy to ≥50% decline i

SUBMITTER: Sim JJ 

PROVIDER: S-EPMC12827094 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature