Case report: From metabolic instability to remission: a case of pheochromocytoma presenting as atypical diabetes.

ABSTRACT:

Introduction

Pheochromocytoma is a well-established cause of secondary hypertension and can lead to dysglycemia. However, its initial presentation as atypical diabetes, characterized by severe glycemic instability, is uncommon and poses a significant diagnostic challenge.

Case presentation

A 49-year-old non-obese Chinese woman presented with a 15-month history of progressive polyuria and polydipsia. Initially diagnosed with type 2 diabetes, she developed significant glycemic variability with recurrent hypoglycemia and profound hyperglycemia, alongside a rapid decline in β-cell function. During hospitalization, paroxysmal hypertension was observed. Biochemical testing confirmed markedly elevated catecholamines and metabolites. Imaging identified a left adrenal mass, confirmed

SUBMITTER: Cao C 

PROVIDER: S-EPMC12827098 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature