Disrupted visual-to-semantic dynamics promote visual hallucinations in Parkinson's disease.

ABSTRACT: Minor hallucinations are frequent and clinically relevant in Parkinson's disease (PD), often preceding cognitive decline and more complex psychotic symptoms. These subtle perceptual anomalies are thought to result from an imbalance between degraded sensory input and dysregulated higher-order cognitive processes. Because visual categorization relies on the integration of perceptual, semantic, and evaluative operations, it provides a powerful framework to investigate the neural mechanisms underlying hallucination vulnerability. Ninety-three non-demented PD patients (mean age = 68.4 years, 41% female) performed a visual categorization task with faces, objects, and face-like stimuli during 19-channel electroencephalography. Patients were classified by hallucination (present/absent) and cogniti

SUBMITTER: Perez-Carasol L 

PROVIDER: S-EPMC12827262 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature