Efficacy of laser acupuncture for patients with knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials.

ABSTRACT: Laser acupuncture (LA) has been increasingly investigated as a non-invasive therapy for knee osteoarthritis (KOA), yet its clinical efficacy remains uncertain. To evaluate the effectiveness and safety of LA for pain, function, and mobility in KOA through a systematic review and meta-analysis. Randomized controlled trials (RCTs) comparing LA with sham, placebo, electroacupuncture, or standard care were identified from major databases. Outcomes included pain (VAS, WOMAC-Pain, NPRS, PI), function (WOMAC-Function), and range of motion (flexion). Risk of bias was assessed using RoB 2, and heterogeneity explored through subgroup analyses. Thirteen RCTs of 611 participants were included. LA did not significantly improve WOMAC pain (SMD 0.04; 95% CI - 0.36 to 0.45), pVAS (SMD 0.12; 95% CI - 0.91 t

SUBMITTER: Kamau VN 

PROVIDER: S-EPMC12827378 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature