Effects of aerobic exercise on cognitive function in older adults with mild cognitive impairment: a systematic review and meta-analysis.

ABSTRACT:

Background

Regular exercise may boost cognition in older adults with MCI, but the effectiveness of different aerobic exercise (AE) modalities is unclear. We conducted a meta-analysis to assess AE's impact on cognition in this group.

Objective

This systematic review and meta-analysis aimed to evaluate the effects of AE on cognitive function in older adults with MCI.

Methods

We searched PubMed, Embase, Web of Science, and the Cochrane Library up to July 2025 and referenced included articles. RCTs with aerobic exercise and outcomes for global cognition and specific cognitive domains in older MCI adults were included. Data was pooled using mean difference, standardized random-effect model, and 95% CI with RevMan V.5.4 and Stata 16.0.

Results

A total of 33 studies w

SUBMITTER: Zhao Q 

PROVIDER: S-EPMC12827630 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature