A comprehensive evaluation of the associations between 12 composite inflammatory indices and all-cause mortality after stroke: a multicohort study.

ABSTRACT:

Background

Inflammation plays a critical role in post-stroke mortality. However, identification of robust and generalizable inflammatory biomarkers for post-stroke mortality remains a challenge. We conducted a comprehensive analysis of various composite inflammatory indices, evaluating the associations between these indices and post-stroke mortality by examining two cohorts, to discover trans-situationally robust indices.

Methods

Data were sourced from the National Health and Nutrition Examination Survey (NHANES) circles of 1999-2010 and 2015-2018, as well as from our stroke center. Twelve composite inflammatory indices were calculated based on peripheral blood cell, C-reactive protein, and albumin. The correlations between these indices and post-stroke mortality were evalua

SUBMITTER: Zheng L 

PROVIDER: S-EPMC12827790 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature