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Preoperative antibiotic prophylaxis in primary shoulder arthroplasty patients: a systematic review.


ABSTRACT:

Background

Cefazolin is the primary antibiotic used for prevention of shoulder arthroplasty (SA) infection. However, vancomycin, clindamycin, and doxycycline may be used, specifically for patients with penicillin allergies or known bacterial colonization. Due to limited existing data, the aim of this systematic review was to characterize contemporary antibiotic prophylaxis choices and report infection rates based on the prophylactic regimen in patients undergoing SA.

Methods

The online databases CINAHL Complete, EMBASE, MEDLINE, the Cochrane Central Registry of Controlled Trials, and Web of Science were searched from database inception to September 25, 2024. Clinical studies comparing preoperative antibiotic regimens and reporting postoperative complications were included. N

SUBMITTER: Liu KC 

PROVIDER: S-EPMC12828191 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature