Iron Deficiency Anemia is Associated With Gastric Intestinal Metaplasia in Patients With <i>Helicobacter pylori</i> Infection.

ABSTRACT:

Background and aims

Despite acknowledgment of the relationship between iron deficiency anemia (IDA) and Helicobacter pylori, consensus is lacking on clinical practice implications. This study sought to examine the association of iron deficiency and anemia with the precancerous lesion gastric intestinal metaplasia (GIM) in a cohort of patients with active H. pylori infection.

Methods

This retrospective cohort was assembled from adult patients diagnosed with H. pylori at endoscopy at Duke University between 2015 and 2019. Data were collected from pathology reports and electronic health records. The relationship between iron deficiency status and GIM prevalence among 422 H. pylori-positive individuals was examined using age-adjusted logistic regressi

SUBMITTER: Patterson S 

PROVIDER: S-EPMC12828382 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature