Risk factors for carbapenem-resistant Acinetobacter baumannii (CRAB) infections in critically ill patients with previous CRAB colonization: a multicentre cohort study.

ABSTRACT:

Background

Among MDR bacteria, carbapenem-resistant Acinetobacter baumannii (CRAB) is a major concern due to the limited therapeutic options.

Objectives

To identify predictors to aid in the clinical management of critically ill patients.

Methods

We conducted a multicentre prospective study in Italy, enrolling patients with CRAB colonization who were admitted to ICUs between 2020 and 2023. Multivariable logistic regression analysis was performed to identify potential risk factors for CRAB infection. To account for competing risks, we used the cumulative incidence function (CIF) and Fine-Gray regression analysis, providing an accurate assessment of the risk of CRAB infection. Additionally, a logistic regression model was performed to estimate the impact of differ

SUBMITTER: Cogliati Dezza F 

PROVIDER: S-EPMC12828430 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature