Survival Benefit and Safety of Anatomic Resection in Cirrhotic Hepatocellular Carcinoma: Propensity-Matched Analysis of 1699 Patients.

ABSTRACT:

Background

The efficacy of anatomic resection (AR) versus non-anatomic resection (NAR) for hepatocellular carcinoma (HCC) remains controversial, particularly among patients with differing underlying liver conditions. This study aimed to compare the outcomes of AR and NAR in HCC patients with and without liver cirrhosis.

Methods

We retrospectively analyzed data from HCC patients who underwent hepatectomy at West China Hospital between 2010 and 2022. Patients were stratified based on the presence of liver cirrhosis. Propensity score matching (PSM) was then applied separately within each stratum (cirrhotic and non-cirrhotic) to compare perioperative outcomes and long-term prognosis between AR and NAR.

Results

A total of 1699 patients were enrolled, including 866 with cir

SUBMITTER: Du A 

PROVIDER: S-EPMC12828670 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature