Which patients with palliative malignant biliary obstruction will benefit most from biliary drainage: Development and validation of a prognostic score.

ABSTRACT:

Background and study aims

Biliary drainage is performed in palliative malignant biliary obstruction (MBO) to improve patient quality of life and enable chemotherapy. This study aimed to create and validate a prognostic score after biliary drainage in patients with palliative MBO.

Patients and methods

Patients undergoing endoscopic or percutaneous drainage for palliative MBO were included in a multicenter, retrospective study. Probability factors associated with 30-day mortality were evaluated by univariable and multivariable logistic regression in the derivation cohort and a prognostic score was built and evaluated in an independent validation cohort.

Results

The derivation cohort included 262 patients, 55% male, 61% of whom had pancreatic adenocarcinoma, mean age 72

SUBMITTER: Olivier R 

PROVIDER: S-EPMC12828974 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature