Malignant solitary fibrous tumor of the temporal bone with NAB2 ex6::STAT6 ex16 fusion: a case report with literature review.

ABSTRACT:

Background

Malignant solitary fibrous tumor is a fibroblastic tumor with rare cases involving head and neck. We herein report a new case in a 73-year-old female patient with a lesion in the right temporal bone, along with a literature review.

Case presentation

A 69-year-old female patient presented to the ENT clinic in 2021 with a three-week history of right-sided otalgia and hearing loss. Incisional biopsy was taken at that time and revealed reactive changes with no evidence of neoplasia. She was lost to follow up until she presented to the clinic again on 2025 with enlarging mass. CT imaging demonstrated a progressively enlarging lytic lesion in the right mastoid bone, measuring 5.5 by 3.0 cm while MRI revealed a large, destructive lesion centered in the right mastoid air

SUBMITTER: Almadan N 

PROVIDER: S-EPMC12829090 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature