Meta-analysis and external validation of a risk model for gastrointestinal bleeding after percutaneous coronary intervention.

ABSTRACT:

Background

Percutaneous coronary intervention (PCI) is a cornerstone in the management of coronary artery disease; however, postoperative gastrointestinal bleeding (GIB) represents a significant complication that adversely impacts patient prognosis. Numerous factors influence GIB, yet no comprehensive meta-analysis has synthesized these to date. Current predictive tools, such as the CRUSADE and PRECISE-DAPT scores, exhibit limited efficacy in forecasting GIB following PCI, underscoring the urgent need for a more precise model to enhance risk management.

Methods

This study employed a meta-analysis to identify risk factors for GIB post-PCI and subsequently developed predictive models based on these findings. The meta-analysis incorporated 77 studies encompassing a total of 7,2

SUBMITTER: Ma H 

PROVIDER: S-EPMC12829118 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature