Biocompatible protein-nanomaterial scaffolds for controlled drug delivery.

ABSTRACT: In this study, a series of collagen-hydroxyapatite (Col-HAp) composite scaffolds in the presence and absence of hexagonal boron nitride (h-BN) were fabricated using a controlled lyophilization technique to fabricate a functional biomaterial for drug delivery application. The lyophilization technique creates an interconnected porous network. The incorporation of h-BN in the Col-HAp/h-BN (1 : 2 : 1) scaffold prominently improved the mechanical strength of the scaffold, reaching 10.27 MPa as compared to the non-loaded h-BN scaffold, thereby enhancing its durability and structural stability. The loading of h-BN also displays a significant increase in surface area (47.27 m² g^-1), gaining abundant active sites for drug encapsulation. Circular dichroism (CD) spectroscopy con

SUBMITTER: Boro B 

PROVIDER: S-EPMC12829313 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature