Bone structure and body composition in adolescents with cow's milk allergy in infancy: a clinical cohort study.

ABSTRACT:

Objective

We compared bone structure and body composition in adolescents with a challenge-confirmed cow's milk allergy (CMA) during infancy to peers with refuted CMA and to controls.

Design

An observational clinical cohort study.

Setting

A tertiary allergy clinic at Helsinki University Hospital.

Patients

From a randomised controlled trial from 1999 to 2001 evaluating the effect of probiotics on atopic eczema, we followed up participants (n=81) at 15-18 years' age and recruited age-matched controls (n=49). Original study participants all had atopic eczema, and CMA confirmed (n=43) or refuted (n=38) by double-blind placebo-controlled cow's milk challenge in infancy.

Main outcome measures

The primary outcome was differences in volumetric bone mineral densit

SUBMITTER: Piippo S 

PROVIDER: S-EPMC12829375 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature