Millisecond-Scale White Matter Dynamics Underlying Visuomotor Integration.

ABSTRACT: In the conventional neuropsychological model, nonverbal visuospatial processing is predominantly handled by the right hemisphere, whereas verbal processing occurs in the left, with right-hand responses governed by the left motor cortex. Using intracranial EEG and MRI tractography, we investigated the timing and white matter networks involved in processing nonverbal visuospatial stimuli, forming response decisions, and generating motor outputs. Within 200 ms of stimulus onset, we observed widespread increases in functional connectivity and bidirectional neural flows from visual to association cortices, predominantly in the right hemisphere. Engagement of the right anterior middle frontal gyrus improved response accuracy; however, the accompanying enhancement in intra-hemispheric connectivit

SUBMITTER: Ueda R 

PROVIDER: S-EPMC12829438 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature