Epidemiology of metabolic syndrome in patients with inflammatory bowel disease: a population-level cohort study from the United States.

ABSTRACT:

Background

Epidemiological data on metabolic syndrome (MetS) in patients with inflammatory bowel disease (IBD) are limited.

Methods

A retrospective cohort study was conducted using the United States (US) Collaborative Network (TriNetX) to obtain data for patients with IBD between 2010 and 2023. The primary aim of the study was to estimate the prevalence of MetS in ulcerative colitis (UC) and Crohn's disease (CD). Prevalence was further characterized by age, sex, race, disease location, IBD medications, history of surgery, and IBD phenotype.

Results

Among 100,890 patients with IBD, metabolic syndrome (MetS) affected 34.4% overall (UC 32.4%, CD 34.3%). Prevalence rose sharply with age (12-14% at 18-39 to 47-50% at ≥65) and was higher in men than women. Rates were greate

SUBMITTER: Desai A 

PROVIDER: S-EPMC12829534 | biostudies-literature | 2025 Nov-Dec

REPOSITORIES: biostudies-literature