Increased brain coverage and efficiency when measuring current-induced magnetic fields by use of simultaneous multi-slice echo-planar MRI.

ABSTRACT:

Purpose

Magnetic resonance current density imaging (MRCDI) can non-invasively validate electric field simulations in volume conductor head models. Weak electric currents are injected using scalp electrodes while measuring the MR phase perturbations caused by the tiny magnetic fields (1-2 nT) induced by the current flow in tissue. MRCDI generally has a low signal-to-noise ratio, making it susceptible to technical imperfections and physiological noise. In this technical note, we tested and optimized simultaneous multi-slice (SMS) EPI for time-efficient and robust brain MRCDI.

Methods

MRCDI data was acquired in a phantom and five human brains using SMS-EPI optimized for measuring current-induced phase perturbations. Multiband factors and interslice gaps were systematically vari

SUBMITTER: Cunha T 

PROVIDER: S-EPMC12829948 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature