Bio-waste derived fluorescent carbon dots based biodegradable mechanically strong hydrogel for stimuli-responsive nonsteroidal anti-inflammatory drug (NSAID) delivery.

ABSTRACT: In this study, biowaste derived carbon dots (BCDs) were synthesized from sugarcane bagasse via a hydrothermal route and incorporated into biodegradable, mechanically robust hydrogels for stimuli-responsive nonsteroidal anti-inflammatory drug (NSAID) delivery. BCDs, characterized by FTIR, Raman spectroscopy, and photoluminescence analyses, exhibited abundant surface functional groups and excellent fluorescence properties. The integration of BCDs into the hydrogel matrix enhanced the mechanical strength, imparted pH-responsive drug release behavior, and maintained the structural integrity under physiological conditions. In vitro release studies using ibuprofen as a model drug demonstrated faster release under acidic conditions (pH 3.8) than under neutral and alkaline pH, aligning with pathol

SUBMITTER: Matalqah SM 

PROVIDER: S-EPMC12829963 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature