Combined [¹⁸F]-FDG PET-MR imaging for monitoring small bowel crohn's disease.

ABSTRACT: Crohn's disease (CD) is a chronic and relapsing inflammatory disease of the gastrointestinal tract. Diagnostics and follow-up are difficult in small bowel, that can be only partially evaluated by conventional endoscopy. Combined positron emission tomography magnetic resonance enterography (PET-MRE) has shown potential in diagnosing small bowel CD, but its role in monitoring treatment response has not been previously established. This study aimed to evaluate whether PET-MRE can be used to assess the efficacy of medical therapy. We hypothesized that standardized uptake values (SUV) in inflamed small bowel segments would decrease following initiation of standard therapy. A total of 35 volunteer patients with clinically suspected small bowel CD were recruited. All patients underwent ileocolono

SUBMITTER: Mattila J 

PROVIDER: S-EPMC12830450 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature