Comparative genomics reveals avian Acinetobacter baumannii as antimicrobial resistance reservoirs and bovine strains with elevated pathogenicity.

ABSTRACT: Multidrug-resistant Acinetobacter baumannii is primarily known as an opportunistic nosocomial pathogen but is increasingly recognized as an emerging contaminant in foods of animal origin. In the present study, we characterized the A. baumannii strains from raw meat samples and undertook a comparative genomic analysis to explore the resistome, virulome, mobilome (integrons and transposons) and pathogenic potential of the A. baumannii strains from food animals and animal origin foods. Avian strains of A. baumannii were found to carry a significantly higher number of antimicrobial resistance genes (P < 0.05) and also possess mobile genetic elements (transposons, integrons), while bovine strains were found to possess significantly higher pathogenic potential (P < 0.05) than A. baumannii strain

SUBMITTER: Bhargavi D 

PROVIDER: S-EPMC12830771 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature