Evolution and Spread of Regionally Adapted Newcastle Disease Virus Isolates From Live Bird Markets in Nigeria, 2023-2024.

ABSTRACT: Newcastle disease (ND) virus (NDV) infection ranks among the most important poultry diseases globally. In Nigeria, ND remains a persistent menace to poultry production, marked by recurrent outbreaks. However, there is limited understanding of the evolutionary changes and transmission dynamics of the virus in the region. A molecular epidemiological study was conducted to elucidate the evolutionary and transmission patterns of NDV in Nigeria. Phylogenetic analysis of seven NDV isolates from cases recorded between 2023 and 2024 in four Northeastern states exhibited genetic diversity and formed distinct clusters that correspond to the prevailing subgenotype XIV.2. The maximum clade credibility (MCC) tree suggests sustained local circulation of the dominant NDV lineage, likely preceded by an in

SUBMITTER: Sajo MU 

PROVIDER: S-EPMC12831130 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature