Localized Choriocapillaris Flow Deficits at Perforating Vessel Sites in Myopic Eyes.

ABSTRACT:

Purpose

To investigate the association between perforating scleral vessels (PSVs) and choriocapillaris (CC) flow deficits (CCFDs) in otherwise healthy myopic eyes, and to identify predictors of localized flow deficits at PSV entry sites.

Methods

PSVs were localized using a combined en face and B-scan approach from swept-source OCTA volumes. CCFD% were quantified from signal-compensated 16-µm en face slabs using the Phansalkar method. Outcome measures included flow deficits at PSV sites (FDPSV), within 250 µm (FD250), and total CCFD. Mixed-effects regression was used to assess associations with demographic, refractive, and anatomic factors.

Results

Fifty-two eyes from 31 healthy myopic (≤-0.5D) participants were included in the study. A total of 119 PSVs were identifie

SUBMITTER: Quarta A 

PROVIDER: S-EPMC12831146 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature