Serotype Prevalence of Group B Streptococcus among Pregnant Women in Iran: A Systematic Review and Meta-Analyses from 2007-2022.

ABSTRACT:

Background

Group B Streptococcus (GBS; Streptococcus agalactiae) is a significant cause of invasive disease in newborns, often stemming from recto-vaginal colonization in pregnant women. The GBS capsular polysaccharide is a major virulence factor, and ten distinct serotypes (Ia, Ib, II-IX) have now been identified. Understanding the prevalence of these serotypes in maternal colonization is crucial for vaccine development. This study aims to determine the serotype prevalence of GBS among Iranian pregnant women.

Materials and methods

A systematic search was conducted in MEDLINE (via PubMed), Embase, Web of Science, and the Iranian Databases (SID and Magiran) for studies published between January 2000 and March 2023. Studies were included if they used standardized

SUBMITTER: Banar M 

PROVIDER: S-EPMC12831592 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature